A Case of Acquired Transient Vitamin K Deficiency in a Teenage Girl

Hye Won Kwon, Sang Heon Lee, Ji Eun Lee, Yeonsook Moon, Soon Ki Kim
2014 Clinical Pediatric Hematology-Oncology  
A 13-year old girl visited emergency medical center presenting with nasal bleeding and gross hematuria. She had no growth retardation, nor history of abnormal bleeding. Her initial blood test results showed normal platelet counts, normal liver enzyme level but prolonged prothrombin time and activated partial thromboplastin time. On admission, she showed massive but intermittent bleeding until the 15 th hospital day. Evaluation including coagulation factor assay was done and the results were
more » ... he results were compatible with vitamin K deficiency. She was treated with vitamin K intramuscular injection 7 times and intermittent transfusion of red blood cells, platelets and fresh frozen plasma. After that, all of her blood test results returned to normal levels including coagulation tests concomitent with resolving symptoms. In that there were no proof of underlying diseases that can cause vitamin K deficiency, she was diagnosed as idiopathic transient vitamin K deficiency. pISSN 2233-5250 / eISSN 2233-4580 http://dx.
doi:10.15264/cpho.2014.21.1.33 fatcat:i66fislc45g2vjtercbnuve52y