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Oleuropein is a fundamental polyphenol contained in olive fruit, oil, and leaf, with a bitter taste. A decrease in its level is observed as the fruit ripens. Leaves of oil tree were used in this study as a possible origin of oleuropein. In this study, cytotoxic, genotoxic, apoptotic and antiangiogenic impacts of isolated oleuropein (0.5xIC 50 , IC 50 and 2xIC 50 ) on MCF-7 human breast adenocarcinoma cells were examined by means of 3-[4,5-Dimethylthiazol-2-yl] 1-2,5diphenyltetrazolium bromidedoi:10.9734/bjpr/2017/33403 fatcat:wyajub4fyva4djcx62ns3elmri