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In this study, solubility and degradation of paracetamol were examined using subcritical water. The effect of temperature and static time was investigated during the solubility process in subcritical water at constant pressure (50 bar). The experimental results showed that temperature and static time have crucial effects on the degradation and solubility degrees. The maximal solubility of paracetamol was obtained at 403 K as (14.68±0.74)×10 3 . An approximation model for the solubility ofdoi:10.2298/jsc160520079e fatcat:xqcryujlrzfuzkc4kzpg2mqoui