Chitosan Nanoparticles have gained more attention as drug delivery carriers because of their better stability, low toxicity, simple and mild preparation method, and providing versatile routes of administration. Their sub-micron size not only suitable for oral application, but also applicable for mucosal routes of administration as well as parental administration, Chitosan Nanoparticles are good drug carriers because of their good biocompatibility and biodegradability, and can be readily

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... . As a new drug delivery system, they have attracted increasing attention for their wide applications. This paper reviews published on Chitosan Nanoparticles, including its preparation methods, modification, and applications.