Prediction of Relative Risk of AIDS Onset (RRA) Using Combined Three-Locus Genotype Data in Bulgarian Population

K. Borissov, A. Savov, R. Argirova
2008 Biotechnology & Biotechnological Equipment  
Here we study the distribution of three HIV-1 resistance conferring polymorphisms -CCR5del32, CCR2-64I and SDF1-3'A in Bulgarian population uninfected with HIV. The relative risk of onset of AIDS symptoms (RRA) is calculated based on this distribution in a representative group of Bulgarians (n=95). RRA was detected to be 0.85 -which falls into the range of this characteristic for the Europeans. The relative risk values similar to that of RRA might be helpful in assessing specific
more » ... ific epidemiological situations in population groups, especially when human genetic factors are involved.
doi:10.1080/13102818.2008.10817594 fatcat:i5jsna5xq5geboam7o2yjhlfhm