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The incidence of oral cancer worldwide is around 500,000 new cases every year, accounting for approximately 3% of all malignancies, thus creating a significant worldwide health problem. The annual incidence and mortality rates vary bet ween different races, genders and age groups. Screen ing and an early detection are believed to decrease both the mor bidity and mortality which are associated with oral squa mous cell carcinoma, because unlike many anatomic sites, in the oral cavity,doi:10.5005/jp-journals-10039-1027 fatcat:a53ejtlw7jcgbpe4lgjk2tfh2e