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Subcellular Trafficking of Mammalian Lysosomal Proteins: An Extended View
2016
International Journal of Molecular Sciences
Lysosomes clear macromolecules, maintain nutrient and cholesterol homeostasis, participate in tissue repair, and in many other cellular functions. To assume these tasks, lysosomes rely on their large arsenal of acid hydrolases, transmembrane proteins and membrane-associated proteins. It is therefore imperative that, post-synthesis, these proteins are specifically recognized as lysosomal components and are correctly sorted to this organelle through the endosomes. Lysosomal transmembrane proteins
doi:10.3390/ijms18010047
pmid:28036022
pmcid:PMC5297682
fatcat:ssdup7vsvzaoth36lzi32fl7tu