Introduction-Sciatic nerve is thickest nerve, arising from L4-S3. It leaves the pelvis through the greater sciatic foramen distal to the Piriformis and descends lateral to the ischial tuberosity, then travels deep to the gluteus maximus and long head of biceps femoris. Anatomical variations of sciatic nerve can contribute to Piriformis Syndrome and sciatica. In addition to the position of the piriformis muscle there other causes for sciatica such as a posterior dislocation of the hip joint,

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... iated disc or pressure from the uterus during pregnancy may damage the nerve roots. A cross-sectional descriptive study conducted at the department of anatomy dissection laboratory, In Bahr dar, Gondar and Mekelle universities. Eighteen adult two female and sixteen male cadavers were dissected from the gluteal region. The total numbers of gluteal regions were 36 used for the study. The courses of sciatic nerve in relation to piriformis muscle were 3 types of course were observed as it comes out of the pelvic to the gluteal. 92% of the cases, sciatic nerve passes below Piriformis muscle.