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The influence of the insect hormone ecdysterone on the composition of the RNA from the fat bodies of Calliphora larvae was investigated by hybridization experiments. DNA was iodinated in vitro with 125J. In saturation experiments, total RNA was hybridized to total DNA; under similar conditions, poly (A) RNA was hybridized to unique DNA sequences. RNA isolated from animals treated with ecdysterone exhibits a higher percentage of hybridization than a corresponding control RNA from the samedoi:10.1515/znc-1977-5-620 fatcat:3c2tjr72nngl7oj6phmbjtsgl4