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Diabetes and Pancreatic Cancer
Research suggests a possible link between type 2 diabetes and several malignancies. Animal models have shown that hyperinsulinemic state underlying diabetes promotes tumor formation through stimulation of insulin-IGF-1 pathway; a possible role of inflammation is also proposed. One such link which has been under considerable study for years is that between diabetes and pancreatic cancer. Although epidemiological evidence points towards a reciprocal link between the two, the cause-effectdoi:10.6092/1590-8577/2680 pmid:25076332 fatcat:43ym5q2d35gg3jtt25pgbxrdty