Distinct Architecture of Lymphatic Vessels Induced by Chimeric Vascular Endothelial Growth Factor-C/Vascular Endothelial Growth Factor Heparin-Binding Domain Fusion Proteins

T. Tammela, Y. He, J. Lyytikka, M. Jeltsch, J. Markkanen, K. Pajusola, S. Yla-Herttuala, K. Alitalo
2007 Circulation Research  
Vascular endothelial growth factor (VEGF)-C and VEGF-D are composed of the receptor-binding VEGF homology domain and a carboxy-terminal silk homology domain that requires proteolytic cleavage for growth factor activation.
doi:10.1161/01.res.0000269043.51272.6d pmid:17478733 fatcat:pqvoj4myizbmvbr5muguzcmrpa