BÖRKÜ M. Kazım
1996 Ankara Üniversitesi Veteriner Fakültesi Dergisi  
Thiacetarsamide sodium application in dogs naturally infected with Dirofilaria immitis Summary: In this study, dirojilariasis caused by Dirojilaria immitis was diagnosed by EL/SA test and Thiacetarsamide sodium was applied to these dogs. Microjilaremi was diagnosed by native blood control in only 2 of 9 dogs which were positive for dirojilariasis in serological control. White dirojilariasis was asymptomatic in 4 dogs coughing, dyspnea, weakness, inappetance and exersize intolerance were the
more » ... erance were the symptoms in 5 dogs. In one dog presenting clinical symptoms; right ventricular hypertrophy dependent jindings in ECG and patchy pulmonary interstitial or alveolar injiltration in thoracic radiographs were observed. Thiacetarsamide sodium was applied i.v. at a dose of 2.2 mg/kg bodyweight with 12 hours intervals for two days to dogs with dirojilariasis. White two of 9 dogs died within 5. and 6. hours exhibiting severe coughing, dy.\pnea, weakness and lethargy after Thiacetarsamide sodium injection. Six dogs didn 't show any important clinical symptoms indicating drug complication. Transitory increase in cough was estimated in one dog. Clinical symptoms, blood analyses (pH, pC0 2 , pOı' SatOı' HCO'.J' Base Status, eryth rocyte, leucocyte and thrombocyte counts, haematocrite, haemoglobine and MCV, blood serum GOT, GPT, total bilirubin, urea, creatinin and albumin values), urine analyses (pH, spesiflc gravity, protein, blood, haemoglobin, bilirubin, urobilinogen, nitrit, glucose), microscopic control of urine, ECG and thoracic radiographic control were peiformed be.fore and after Thiacetarsamide sodium application. ELlSA test was repeated 2 months after therapy was complated. As a result, it is stated that ELlSA test will be able to be useful for the diagnosis of dirojilariasis caused by Dirojilaria immitis in dogs and Tlıiacetarsamide sodium is an effective drug againts dirofilariasis according to the ELlSA test results peiformed 2 months after therapy.
doi:10.1501/vetfak_0000000701 fatcat:ktgqvvhqqbdarjtyeyd55fac5q