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The purpose of this study was to examine the effect of dexamethasone (Dex) treatment and electrical stimulation (ES) on skeletal muscle cell derived exosome's microRNA (miR) profile and its effect on skeletal muscle signal protein expression. Exosome obtained from two different C2C12 cell were treated with Dex or ES. Then we profiled exosome's miR expression and atrophy related miR-1, miR-206, miR-322 were significantly increased with DEX however, hypertrophy related miR-23a was significantlydoi:10.15857/ksep.2014.23.4.347 fatcat:aeq44cg65vex3c56o5zuurx6na