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According to the published articles, there is an increase in the prevalence of MS all over the world. Regarding demographic characteristics for unknown reasons, females are more affected than males. Objectives: The aim of this study was demographic analysis and model of changes in patients for three years in a local teaching hospital in Isfahan/Iran. Patients and Methods: In total, 1500 patients with MS were studied within three Intervals (I) from; I3. Data was recorded in Excel and analyzeddoi:10.5812/archneurosci.21806 fatcat:vu33u5gvynh7xcmgj5cmuwb3za