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Multi-site clinical trials are essential within medical practice to help drive reliable and generalizable knowledge on advancing medical treatments. Although the success of multi-site trials is significantly dependent on local clinician and site research teams, best practices for engagement of site teams, or "site engagement," has not been extensively discussed. Site engagement centers on including sites in the planning and implementation of clinical trials to promote trial enrollment,doi:10.1016/j.conctc.2020.100608 pmid:32685765 pmcid:PMC7358177 fatcat:p3tjl2atevggfnpu7ixyiyqkfe