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Clustering by common friends finds locally significant proteins mediating modules
2007
Bioinformatics
Motivation: Much research has been dedicated to large-scale protein interaction networks including the analysis of scale-free topologies, network modules and the relation of domain-domain to protein-protein interaction networks. Identifying locally significant proteins that mediate the function of modules is still an open problem. Method: We use a layered clustering algorithm for interaction networks, which groups proteins by the similarity of their direct neighborhoods. We identify locally
doi:10.1093/bioinformatics/btm064
pmid:17314122
fatcat:e2qs6bp34rhojhr26qumabalbe