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Genes & Development
Recent interest in modeling biochemical networks raises questions about the relationship between often complex mathematical models and familiar arithmetic concepts from classical enzymology, and also about connections between modeling and experimental data. This review addresses both topics by familiarizing readers with key concepts (and terminology) in the construction, validation, and application of deterministic biochemical models, with particular emphasis on a simple enzyme-catalyzeddoi:10.1101/gad.1945410 pmid:20810646 pmcid:PMC2932968 fatcat:d6nhsqygsrgpxok26lyq2g5xry