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A rapid, reproducible and accurate TLC method was developed for the determination of Cetirizine Dihydrochloride in tablet. Th e analytes were dissolved with ethanol 70% and chromatographed on silica Gel GF 254 TLC plate using chloroform : methanol : ethyl acetate in the ratio of 2 : 7 : 3 (v/v) as mobile phase. Quantitative analysis was done through densitometric measurement at wavelength 234 nm. Method was found linear over the concentration range of 400 -1600 ng/spot with the correlationdoi:10.3329/icpj.v3i1.17294 fatcat:zek4ewmipbe6dgvhazou742ahe