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In the recent years, there is a paradigm shift in the management of necrotic immature permanent teeth, with most of these teeth being treated by revascularization rather than conventional apexification procedure. Current regenerative endodontic protocols (REP) emphasizes the need to have a disinfection protocols that will enable good disinfection without causing damage to stem cells. The current available evidence suggest that true pulp-dentin complex is not being formed after REP, neverthelessdoi:10.5005/jp-journals-10047-0006 fatcat:btoslzp7unb4naekaxn3s3ii54