Hepatic decompensation associated with an interferon-free antiviral therapy in patients with HCV-cirrhosis

S N Batskikh, E V Vinnitskaya, Yu G Sandler, T Yu Khaimenova
2018 Терапевтический архив  
Today, there is no complete clarity about the pathogenetic mechanisms of the hepatic decompensation in patients with HCV-cirrhosis during the course of direct-acting antiviral (DAAs) therapy. The current article describes several clinical observations of decompensation (with the development of liver failure and portal hypertension) in cirrhotic patients during the course of DAAs-therapy of hepatitis C. The authors present contemporary views and their own assumptions about the possible
more » ... of the hepatic decompensation associated with DAAs-therapy in patients with liver cirrhosis.
doi:10.26442/terarkh201890114-73 pmid:32598651 fatcat:f6zuambjs5byjobd2tt6bs3xse