Population Attributable Fractions of Caffeine and Water Pipe on Low Birth Weight: A Population-Based Prospective Cohort Study in Iran [post]

Shahrzad Nematollahi, Mohammad Ali Mansournia, Abbas Rahimi-Foroushani, Ali Mouseli, Hossein Shabkhiz, Koroush Holakouie-Naieni
2020 unpublished
BackgroundTo estimate Population Attributable Fractions (PAFs) and Generalized Impact Fractions (GIFs) for LBW following scenarios to remove or decrease prenatal use of caffeine or water pipe.Methods‎Using data of 861 pregnant women from a population-based prospective cohort study ‎in suburbs of Bandar Abbas city (2016-2018), PAFs and GIFs were calculated based on the relative risk scale. Practical interventional scenarios to reduce the exposure prevalence were developed for calculation of
more » ... calculation of GIFs. ResultsThe cumulative incidence of LBW was 16.1%. An estimated 19% (95%CI: 6, 30%) of LBW neonates was attributed to dietary caffeine intake of >100 mg/day and 11% (95%CI: 8,14%) to water pipe smoking. Action plans to reduce caffeine intake and water pipe smoking suggested an avoidable burden of LBW cases of approximately 10.7% (95% CI: 6.6, 25.3%) and 5.7% ‎‎(95%CI: ‎5.0, 6.8%), respectively.‎ConclusionsWater pipe smoking and excessive consumption of caffeine during pregnancy decreased birth weight. Practical action plans to control water pipe smoking ‎and to prevent excessive intake of ‎caffeine ‎among pregnant women would substantially reduce LBW burden in the south of Iran. ‎
doi:10.21203/rs.3.rs-116692/v1 fatcat:dnsdkvwlibecvk5ehp7wwbldi4