The purpose of the present study is to identify predisposing factors and direction of dislocation of the natural crystallinelens or intraocular lens (IOL) in IOL intrascleral fixation surgery and determine changes in intraocular pressure (IOP) after surgery. We retrospectively investigated predisposing factors, direction of the lens, IOL dislocation, and IOP preoperatively and 1 day, 1 week, and 1 month postoperatively in 240 eyes from 232 patients who underwent IOL intrascleral fixation. The

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... rgery was performed in 48 patients with long eye axis, 44 with pseudoexfoliation (PE), 42 with intraoperative problems, 40 with a history of trauma, 34 with a history of vitrectomy, 21 with atopic dermatitis, 6 with genetic diseases, 4 with retinitis pigmentosa, and 56 with unknown causes. Downward IOL dislocation was most observed (52 cases), while IOL falling into the vitreous cavity was seen in 46 cases, aphakic eye in 31 cases, and anterior lens dislocation in 16 cases. In general, IOP was significantly lower at 1 month postoperatively than preoperatively; specifically, in the PE, history of trauma, atopic dermatitis, long eye axis, and unknown cause groups, as well as the groups with anterior lens deviation, IOL fall into the vitreous cavity, and IOL downward deviation.