A novel method for predicting protein subcellular localization based on pseudo amino acid composition

Junwei Ma, Hong Gu
2010 BMB Reports  
In this paper, a novel approach, ELM-PCA, is introduced for the first time to predict protein subcellular localization. Firstly, Protein Samples are represented by the pseudo amino acid composition (PseAAC). Secondly, the principal component analysis (PCA) is employed to extract essential features. Finally, the Elman Recurrent Neural Network (RNN) is used as a classifier to identify the protein sequences. The results demonstrate that the proposed approach is effective and practical. [BMB
more » ... ctical. [BMB reports 2010; 43(10): 670-676]
doi:10.5483/bmbrep.2010.43.10.670 pmid:21034529 fatcat:pf6tmbx42vbybe624lvuclv4my