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Effect of central corticotropin-releasing factor on carbon tetrachloride-induced acute liver injury in rats
American Journal of Physiology
Central neuropeptides play important roles in many instances of physiological and pathophysiological regulation mediated through the autonomic nervous system. In regard to the hepatobiliary system, several neuropeptides act in the brain to regulate bile secretion, hepatic blood flow, and hepatic proliferation. Stressors and sympathetic nerve activation are reported to exacerbate experimental liver injury. Some stressors are known to stimulate corticotropin-releasing factor (CRF) synthesis inpmid:10070038 fatcat:rj2iyfbqnng7nces6gjmncfzz4