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Production of Human Interferon β by Recombinant E. coli Using the Codon Optimized Gene
코돈 최적화된 유전자를 이용한 재조합 대장균으로부터 인간 인터페론 베타 발현
2017
KSBB Journal
코돈 최적화된 유전자를 이용한 재조합 대장균으로부터 인간 인터페론 베타 발현
Preserved Fulltext
The multiple sclerosis caused by multiple inflammatory disease or immune system disorder, is usually treated by interferon β through adjusting the abnormal immune reactions. For high production of human interferon β using recombinant E. coli, codon optimized and wild type genes were synthesized. When pET-15b or pET-21a vector was used as an expression vector with each gene, there was no target protein expression. When pQE30 vector was used as an expression vector, human interferon β was
doi:10.7841/ksbbj.2017.32.1.16
fatcat:tmmnufsmnvdxxo53kvsquflq4u