The value of urine samples from men with non-gonococcal urethritis for the detection of Chlamydia trachomatis

P E Hay, B J Thomas, C Gilchrist, H M Palmer, C B Gilroy, D Taylor-Robinson
1991 Sexually Transmitted Infections  
Chlamydia trachomatis was sought at first and subsequent clinic visits in urethral swabs and urines from 112 heterosexual men with acute non-gonococcal urethritis (NGU). In comparison with a urethral swab tested by MicroTrak (MT), a urine deposit tested in the same way was 90% as sensitive. Examining a urine deposit by the enzyme immunoassay IDEIA was a little less sensitive (89%) than examining a similar deposit by MT, and was less sensitive (82%) than examining a urethral swab by MT. The
more » ... wab by MT. The results oftesting urines were little influenced by collecting them either before or after swabbing the urethra, and there was evidence that examining all of a urine sample by IDEIA would have increased sensitivity. Overall, 55 (49%) of the men were diagnosed as C trachomatis-positive based on the results of testing both a urethral swab and a urine sample. Furthermore, small numbers of chlamydiae were detected by examining urine by MT and, to a lesser extent, by IDEIA, so that there is no reason why this non-invasive approach should not be successful in men other than those with acute NGU. on 23 July 2018 by guest. Protected by copyright.
doi:10.1136/sti.67.2.124 fatcat:k6f3cpfhg5frdpjrccfge72o3e