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Hepatitis C virus (HCV) infects ≈2% of the world's population. HCV infection not only causes acute and chronic hepatitis, but also leads to liver cirrhosis and hepatocellular carcinoma (HCC). The molecular pathogenesis of HCV infection has been explored and many evidence indicated that autophagy is an important process for its life cycle, although autophagy was thought as a mechanism to eliminate invaded HCV from hepatocyte. Structural and non-structural proteins of HCV are important regulatorsdoi:10.1515/ii-2017-0001 fatcat:56ueycfz3ve3tjvfvor25ais44