Reinke´s Crystals in Perivascular and Peritubular Leydig Cells

Viviana Kozina, Ljerka Banek, Nikola Knežević, David Geist, Lucie Kubinová, Marin Kosović, Christian Rentenberger, Andreja Vukasović, Davor Ježek
2011 Croatica Chemica Acta  
The human testis is composed of seminiferous tubules and interstitium. Within the interstitium, residing Leydig cells can occasionally bear Reinke´s crystals. The aim of the current study was to investigate Reinke´s crystals in perivascular and peritubular Leydig cells in control and infertile (cryptorchid) testes. For that purpose, bright field, confocal and transmission electron microscopy were applied. The crystal lattice was investigated by Fast Fourier Transformation and the number of
more » ... the number of crystals determined by stereology. Results of the study indicated a higher number of crystals in perivascular cells (in the both control and cryptorchid group). Moreover, when control and cryptorchid specimens were compared for the presence of the crystal, a higher number of Reinke´s crystals was recorded in cryptorchid testes. Thick sections of the crystal were extremely helpful in yielding crystallographic data which confirmed a trigonal crystal structure of the lattice. The exact molecular composition of crystal's microfilaments still remains unknown. (doi: 10.5562/cca1814)
doi:10.5562/cca1814 fatcat:seeenxjilfb53gl33gtrjwhnwe