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Consciousness has been related to the amount of integrated information that the brain is able to generate. In this paper, we tested the hypothesis that the loss of consciousness caused by propofol anesthesia is associated with a significant reduction in the capacity of the brain to integrate information. To assess the functional structure of the whole brain, functional integration and partial correlations were computed from fMRI data acquired from 18 healthy volunteers during restingdoi:10.1016/j.neuroimage.2011.04.020 pmid:21524704 fatcat:nkgbtumcwrba7er7g25utmchqq