Quantitation of excretion of dolichol and dolichyl phosphate from the rat

Lorraine W. Connelly, R. Kennedy Keller
1984 Bioscience Reports  
In order to gain information on the metabolism of dolichol, the rates of excretion of dolichol and doJichyl phosphate were determined in rats maintained on a dolichol-free diet :for l0 days. Analysis of fecal samples collected every 4g h yielded mean output values of 9.0 -+ 1,4 and 20.7 _+ 3,0 pg/rat/day of dolichot and dolichy] phosphate, respectively. Urinary output rates were 0.56 -+ 0.12 and 0.50 -+ 0.2g IJg/rat/ day of dolichol and dolichyt phosphat% respectively. Thus~ excretion is one
more » ... excretion is one fate of endogenously synthesized dolichoI compounds in the rat.
doi:10.1007/bf01128818 pmid:6509160 fatcat:fyogw4cizng63ncczlac4nlssq