5. RETHINKING THE TAXONOMY, COURSE, AND OUTCOME OF PSYCHOSES: DIMENSIONAL, LATENT TRAJECTORY, AND TRANSDIAGNOSTIC APPROACHES
Results: UHR pilot: System usage was high, with a total 270 logins (18/ user), 749 posts (58/user), 170 therapy modules completed (12/user), and 67% of users being actively engaged over the trial. All participants reported a positive experience using Momentum and would recommend it to others. 93% considered Momentum to be helpful. Analysis revealed a significant increase in social functioning (p<0.001; d=2.39) and satisfaction with life (p=0.03; d=0.48) at follow-up. There was a significant
... s a significant increase in therapy mechanisms directly targeted by Momentum including strengths usage (p=0.03; d=0.46), mindfulness skills (p=0.04; d=0.36) and components of social support. There were significant correlations between system usage and improvements in social functioning (r=0.63 p=0.02), social support (r=0.62 p=0.02) and strengths usage (r=0.51 p=0.06). FEP pilot: system use was high. The majority of FEP participants reported feeling safe (100%) and more socially connected (60%) using Horyzons. There was a significant reduction (d=0.60; p=0.03) in depressive symptoms at follow-up. FEP RCT: Horyzons' safety outcomes have been consistently strong. System usage is being high, with an average 101 logins, 70 posts, and 11 therapy modules per user, and 60% of users being engaged with the online system for a period of 18 months. Discussion: Horyzons and Momentum are the first online interventions designed to improve functional outcomes in FEP and UHR patients. Momentum is engaging, safe, may improve social functioning and satisfaction with life in UHR patients and appeared to specifically improve therapeutic mechanisms directly targeted by the online intervention. Horyzons is safe and engaging (over prolonged periods of time) and may improve depression and social connectedness in FEP patients.