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To microbiologists, the term macroecology may conjure iconic images of wildebeests grazing in African savannahs or hummingbirds pollinating flowers in a tropical rain forest. Contrary to what the name implies, macroecology is not the ecological study of macroscopic organisms. Rather, macroecology is the study of ecological relationships through patterns in abundance, distribution, and diversity. In this paper, we highlight some of the pressing questions, challenges, and opportunities for microbial macroecology.doi:10.7287/peerj.preprints.2478 fatcat:vwe3ujabhrhz5alca3utqvmb3y