Safety, efficacy, and tissues residues of ivermectin in reindeer

Robert A. Dieterich, Arthur L. Craigmill
1990 Rangifer  
Safety, efficacy, and tissue residues of ivermectin, a broad spectrum parasiticide, were determined in Alaskan reindeer (Rangifer tarandus). Reindeer treated at 5 times and 10 times the standard dose of 200 mcg/kg had no detectable physical or behavioral reactions to ivermectin injected subcutaneously in the mid-cervical area. Ivermectin eliminated essentially 100% of reindeer warble larvae (Hypoderma (Oedemagena) tarandi). Tissue levels of ivermectin in back fat, injection site, muscle, liver,
more » ... and kidney collected 3, 10, 17, and 24 days post injection were determined. All tissues levels rapidly declined and were approaching low unmea-surable amounts at the end of the 24 day test period. Ivermectin is a safe effective parasiticide that has been used successfully to threat thousands of reindeer in Alaska.
doi:10.7557/ fatcat:4qbcrvuje5c5dfbhuzktthravy