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The aim of the present study was to formulate and evaluate the ritonavir-loaded stealth liposomes by using 3 2 factorial design and intended to delivered by parenteral delivery. Liposomes were prepared by ethanol injection method using 3 2 factorial designs and characterized for various physicochemical parameters such as drug content, size, zeta potential, entrapment efficiency and in vitro drug release. The optimization process was carried out using desirability and overlay plots. The selecteddoi:10.1007/s13204-015-0408-8 fatcat:mnoj66l5vbdsflmszuqzxz4xza