Cardiovascular Risk in Patients with Subclinical Hypothyroidism

Leonidas H Duntas, Luca Chiovato
2014 European Endocrinology  
Subclinical hypothyroidism (SCH) has been associated with increased cardiovascular mortality due to adverse effects mainly on lipids and blood pressure (BP). There is evidence that SCH, especially in patients with thyroid-stimulating hormone (TSH) >10mU/l, may increase cardiovascular risk. Some uncertainty exists regarding the association of SCH with BP; however, that the coexistence of SCH with BP and hypercholesterolaemia has a negative cardiovascular impact is beyond doubt. Insulin
more » ... , by modulating various risk factors including coagulation, may potentially increase cardiovascular risk. Periodic health examinations including screening has been advised in patients >35 years of age, while treatment with thyroxine should be tailored to each patient.
doi:10.17925/ee.2014.10.02.157 pmid:29872482 pmcid:PMC5983087 fatcat:3lztyh6oinb75mkcivofut6kwm