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The clinical case of the patient with prevalence of extraintestinal manifestations (dermatological) of nonspecific ulcerative colitis is discussed. The diagnostic of nonspecific ulcerative colitis with insignificant intestinal symptomatology is very difficult. A correct estimation of all symptoms is promoting the timely diagnostic. This is leads to early administration of appropriate therapy, and allows to get the remission of ulcerative colitis.doi:10.17816/clinpract3336-41 fatcat:4a7x3s4rfnd2tg37ukfelr4yuy