HORMONAL STATUS AND SPERMIOLOGICAL PARAMETERS OF MEN WITH MICROSURGERY FOR NON-OBSTRUCTIVE AZOOSPERMIA

M. L. Panasovsky
2020 Zenodo  
Panasovsky M. L. HORMONAL STATUS AND SPERMIOLOGICAL PARAMETERS OF MEN WITH MICROSURGERY FOR NON-OBSTRUCTIVE AZOOSPERMIA. Актуальні проблеми транспортної медицини / Actual problems of transport medicine / 2020;1(59):65-71. ISSN 1818-9385 DOI http://dx.doi.org/10.5281/zenodo.3744367 http://aptm.org.ua HORMONAL STATUS AND SPERMIOLOGICAL PARAMETERS OF MEN WITH MICROSURGERY FOR NON-OBSTRUCTIVE AZOOSPERMIA Panasovsky M. L. Kharkiv National Medical University; Kharkiv Regional Clinical Center of
more » ... cal Center of Urology and Nephrology. Email: panas26031973@gmail.com Summary The objective: The purpose of the study was to evaluate hormonal levels and spermological parameters of men with microsurgery for non-obstructive azoospermia (NA). Materials and methods. Medical cards of 45 men with NA were analyzed and micro-TESE was performed from 2016 to 2019. Patients' age, hormonal profile (follicle-stimulating hormone (FSH), luteinizing hormone (LH), and testosterone (TT) levels) were analyzed and the morphological and functional characteristics of the obtained spermatozoa were determined. Results. Spermatozoa were extracted in 10 (22%) patients with HA. As, The probability of sperm production decreases with patients' age increase. The average concentration of spermatozoa in samples was (2.3 ± 0.8) million, (18.0 ± 0.3)% of them were active motile. Morphological analysis of sperm revealed that head abnormalities was (19.9 ± 2.45)%, the neck abnormalities was (13.69 ± 1.49)% and tail abnormalities was (5.96 ± 1.52)%. Mixed pathology rate included head, neck and middle part abnormalities was (34.6 ± 4.21)%. Conclusions. Spermatozoa were obtained during micro-TESE for further use in ART programs in 22.2% of men with NA despite high level of FSH and LH. Spermatozoa were retrieved significantly more often in a group of young patients with high level of testosterone. Key words: azoospermia; non-obstructive azoospermia; sperm.
doi:10.5281/zenodo.3744366 fatcat:gbwclc72e5fwhpns7dew5insrq