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The twilight zone of cis element alignments
2012
Nucleic Acids Research
Sequence alignment of proteins and nucleic acids is a routine task in bioinformatics. Although the comparison of complete peptides, genes or genomes can be undertaken with a great variety of tools, the alignment of short DNA sequences and motifs entails pitfalls that have not been fully addressed yet. Here we confront the structural superposition of transcription factors with the sequence alignment of their recognized cis elements. Our goals are (i) to test TFcompare
doi:10.1093/nar/gks1301
pmid:23268451
pmcid:PMC3561995
fatcat:oeohciho5ze7vbarqoogqidbfu