Ritter-Enabled Catalytic Asymmetric Chloroamidation of Olefins

Daniel C. Steigerwald, Bardia Soltanzadeh, Aritra Sarkar, Cecilia C. Morgenstern, Richard J. Staples, Babak Borhan
2021 Chemical Science  
Intermolecular asymmetric haloamination reactions are challenging due to the inherently high halenium affinity (HalA) of the nitrogen atom, which often leads to N-halogenated products as a kinetic trap. To circumvent...
doi:10.1039/d0sc05224h pmid:34163947 pmcid:PMC8179065 fatcat:p2goetykqjayflhzmy7fsgvdq4