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Interleukin-6 blockade improves autonomic dysfunction in rheumatoid arthritis
Acta Reumatológica Portuguesa
Autonomic nervous system (ANS) involvement in rheumatoid arthritis (RA) is well recognised and contributes to arrhythmia and sudden death. However, there is no study documented the therapeutic efficacy on autonomic neuropathy (AN) in RA. This is the first reported observation of improvement in AN with interleukin-6 (IL-6) blockade with tocilizumab in RA. We report a case of 61-year old female with seropositive RA with severe disease activity, investigated for autonomic neuropathy. A battery ofpmid:24863079 fatcat:75r37judsjcd5oyrd33kbukfcy