Secondary syphilis presenting as Syphilide psoriasiforme: lessons from the older syphilology literature

Carlos José Martins, Ricardo Barbosa Lima, Walter de Araujo Eyer-Silva, Camila Bastos Almenara, Isabelle Carvalho-Rangel, Ricardo de Souza Carvalho, Rodrigo Panno Basílio-de-Oliveira, Luciana Ferreira de Araujo, Fernando Raphael de Almeida Ferry, Leila Rangel da Silva
2020 Revista do Instituto de Medicina Tropical de São Paulo  
It is essential for health care providers to be familiared with the full spectrum of clinical presentations of syphilis. We present herein a case of syphilide psoriasiforme, an uncommon but well recognized clinical presentation of secondary syphilis. A 46-year-old HIV-infected female patient was referred to our attention with a presumptive diagnosis of palmoplantar psoriasis. On examination, there were exuberant pinkish-red papules and plaques covered with a thick silvery scale in the palms,
more » ... le in the palms, flexor surfaces of the wrists, and the medial longitudinal arches of the feet. Serological and histopathological analyses uncovered the diagnosis of syphilis. Clinical remission was obtained after treatment. A detailed review of the literature on syphilide psoriasiforme, including descriptions from older syphilology textsis provided. The present case report emphasizes the need for clinicians to have a heightened awareness of the varied and unusual clinical phenotypes of syphilis.
doi:10.1590/s1678-9946202062021 pmid:32236388 fatcat:le356a5i3vh4nk6c57iigtodvy