Correlation of Serum and Urine Sialic Acid Levels with Lipid Profile and Anthropometric Indices in Type 2 Diabetes Mellitus and Diabetic Nephropathy

K. Prajna, Srinidhi Rai, Tirthal Rai
2018 International Journal of Biochemistry Research & Review  
Sialic acid is a component of vascular cell membranes; the elevated levels indicate excessive vascular damage leading to diabetic complications. Therefore sialic acid can be considered to be newly established potential risk factor for the development of diabetic nephropathy. Aims: To study the correlation between sialic acid levels with lipid profile and anthropometric variables in type 2 diabetes mellitus and type 2 diabetics with nephropathy. Study Design: Case control study Place and
more » ... y Place and duration of study: study was conducted at department of biochemistry and department of medicine at aj institute of medical sciences, mangalore for a period of 2 years. Methodology: Study population included 75 subjects in the age group of 40-70 years out of whom 25 subjects were type 2 diabetics (newly diagnosed or known diabetics on treatment without any complications), 25 subjects were type 2 diabetics with nephropathy and 25 were age and sex matched normal controls. Serum and urine sialic acid, lipid profile and anthropometric variables were measured in study subjects. Original Research Article
doi:10.9734/ijbcrr/2018/43386 fatcat:e4gvahmcyjb4jhzgfuiy23rpty