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FOXP3+ regulatory T cells and the immune escape in solid tumours
Frontiers in Immunology
FOXP3+ regulatory T (Treg) cells play critical roles in establishing the immunosuppressive tumour microenvironment, which is achieved and dynamically maintained with the contribution of various stromal and immune cell subsets. However, the dynamics of non-lymphoid FOXP3+ Treg cells and the mutual regulation of Treg cells and other cell types in solid tumour microenvironment remains largely unclear. In this review, we summarize the latest findings on the dynamic connections and reciprocaldoi:10.3389/fimmu.2022.982986 pmid:36569832 pmcid:PMC9774953 fatcat:p7yp4q34fjfhlkompr334aaxcq