"DIAGNOSTIC ROLE OF PLEURAL BIOPSY IN EXUDATIVE PLEURAL
BACKGROUND: Exudative pleural effusion poses a diagnostic challenge, main differentiation being TB and malignancy. The role of needle biopsy varies in different patient groups and is likely to be of greater benefit in countries with high TB prevalence. OBJECTIVE: To evaluate diagnostic yield of Abraham pleural biopsy in cases with exudative pleural effusion. METHODOLOGY: A descriptive study was conducted in Jinnah Hospital Karachi, department of chest medicine from September 2007 to March 2009.
... 2007 to March 2009. Seventy nine patients of age> 12 years diagnosed with exudative pleural effusion were consecutively enrolled. Pleural biopsy was performed by Abrams biopsy needle. The main outcome of the study was to evaluate diagnostic yield of Abraham needle biopsy. RESULTS: The mean age of the sample was 47.55±18.56 years. There were 49 (62%) males and 30 (39%) were females. The results found that pleural biopsy was diagnostic in 50 (63.29%). Out of 50 patients, 21 (42%) patients had tuberculosis Ward 12, Department of Chest Medicine, Jinnah Post Graduate Medical Center, Karachi and 18 (36%) malignancy. Chronic non specific inflammation was present in 6 (12%) of patients and empyema in 5 (10%) patients. CONCLUSION: Abraham needle biopsy is useful in confirming the diagnosis of TB and malignancy in patients with exudative pleural effusion.