OBJECTIVE: Mother to child transmission of HIV is a major route of HIV infection in children. The objective of this study is to analyze the response to implementation of PPTCT programme, the response of the spouses of the seropositive antenatal women to undergo HIV testing, mode of delivery and breast feeding practices adopted by the seropositive postnatal women and the status of infants after delivery at 18 months. a period of 5 years was studied. PPTCT centre was established in our

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... in 2003. The practice in our institution is that all pregnant women attending the Antenatal clinic or Labour Room are counseled for HIV testing, and tested as per NACO guidelines. Babies born to HIV seropositive women are followed up to 18 months for confirmatory testing. RESULTS: The number of antenatal women counseled who opted for HIV testing were 99.4% and women who tested seropositive was 1.6 %, 1.3%, 0.9%, 0.84%, 0.6% for the years 2009-10, 10-11, 11-12, 12-13, 13-14 respectively showing a declining trend in the prevalence of HIV in antenatal women. 94.6% of women attended the post-test counseling. Spouses of seropositive antenatal women who opted for testing was 52.5% and seropositivity in the spouses tested was 65.87% during the study period. Of the 767 seropositive women who delivered, 542(70.66%) had vaginal delivery 225(29.33%) had LSCS for obstetric indication. Of the 767 seropositive women who delivered 719(93.7%) had live births, 28(3.65%) had intrauterine fetal demise and 20(2.6%) newborns died in the perinatal period. The number of seropositive women opting for exclusive replacement feeding was 54.4% during the study period April 2009 to March 2014. Confirmatory test for infants was done at 18 months and of the 136 infants tested, 14 were found to be seropositive. CONCLUSION: With effective implementation of PPTCT programme, HIV infection in antenatal women is showing a decreasing trend. Women are willing to undergo HIV testing but their spouses need to be counseled for coming to the antenatal clinic for testing.54% of women who were seropositive are opting for exclusive replacement feeding which may contribute to bring down the incidence of HIV in newborn, but as most of the antenatal patients are from the low socio economic status, reinforcement of counseling regarding exclusive breast feeding needs to be done. The seropositive status of the newborns is about 10.29% during the study period which can be brought down still further by initiation of triple drug ART Regimen for all pregnant women.