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Running downhill improved the expression of glucose transporter 1 (Glut 1) and fasting blood glucose in mouse. Eccentric contraction during running downhill found daily in activity such as down stairs and walking on tiptoe. Descend the stairs and walking on tiptoe are not easy to repeated, single, stable and universal, so that we purposed to replace it with additional insole in shoes for daily activity. The aim of this research was to investigate the effect of the additional shoe insole ondoi:10.20473/jn.v11i12016.29-33 fatcat:ob3b2hnhcra3lhmyjorthegpo4