To re-examine the validity of the medical knowledge that are embedded in the legacy system, we translated a Medical Logic Module (MLM) for hyperkalemia patient screening into the GuideLine Interchange Format (GLIF). We used a set of guiding principles to direct the translation. In addition, we used the GLIF3 Guideline Execution Engine (GLEE) as a testing tool to validate the encoded GLIF guideline by applying it to 5 simulated patient cases. The result has shown that it is possible to translate

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... Arden MLMs into GLIF guidelines. However, significant efforts are necessary to handle the problems arose during the translation process. Automatic translation could be a more generalizable approach for future work.