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Since in health care systems the amount of data is continuously growing, data mining techniques can be applied to analyse these large collections and gain interesting insights. However, some critical issues should be properly addressed. For example, data collections on patient treatments are usually characterized by an inherent sparseness and variable distribution, due to the large variety of possible treatments performed by patients affected by a given disease. To effectively extractdblp:journals/cib/XiaoC14 fatcat:kpikzxeiajf35kjciemgx7p4gm