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Data-driven approaches to advance research and clinical care for pediatric cancer
2021
Biochimica et Biophysica Acta. CR. Reviews on Cancer
Pediatric cancer is a rare disease with a distinct etiology and mutational landscape compared with adult cancer. Multi-omics profiling of retrospective and prospective cohorts coupled with innovative computational analysis have been instrumental in uncovering mechanisms of tumorigenesis and drug resistance that are now informing pediatric cancer clinical therapy. In this review we present the major data resources of pediatric cancer and actionable insights into pediatric cancer etiology
doi:10.1016/j.bbcan.2021.188571
pmid:34051287
fatcat:xr457oomkrfirm5lzkbn5nkgpy