Histopathological spectrum of external ocular lesions

Asuman Kilitci
2019 The Annals of Clinical and Analytical Medicine  
Aim: The aim of this study was to examine the materials of the patients who received biopsy for mass in the anatomical regions (medial, lateral, inferior, superior, eyebrow, and canthus) next to the eyelid and conjunctiva. Material and Methods: The frequency, clinical and histopathologic characteristics of these materials were determined. The data on 258 lesions in and around the eyes of 233 patients were screened. Results: A total of 107 (46%) of the patients were male and 126 (54%) were
more » ... . The age range of the patients was 11-89 and the average age was 49. A total of 227 of 258 lesions (88%) were benign, 23 (8.9%) were malignant, 8 were (3,1%) premalignant (6 actinic keratoses, 1 keratoacanthoma, 1 conjunctival IN). A total of 19 of the malign lesions were basal cell carcinoma (BCC), 3 were squamous cell carcinoma (SCC), and 1 was Basosquamous carcinoma (BSC). Among the benign lesions, the most commonly-made histopathologic diagnoses were intradermal nevus (n:46, 20.2%), epidermal cyst (n:31, 13.7%), fibroepithelial polyp (n:28, 12.3%), squamous papilloma (n:25, 11.0%), seborrheic keratosis (n:21, 9.3%), xanthelasma (n:20, 8.8%), and verruca vulgaris (n:20, 8.8%). Intradermal nevus and xanthelasma were significantly more in women (p<0.05). In men, on the other hand, epidermal cyst and fibroepithelial polyp were significantly higher. Discussion: Although external masses in and around the eye mostly appear before us as large benign lesions, they must be confirmed with clinical imaging and histopathologic examination. Due to esthetic concerns and small size of the lesions, they may lead to difficulties in terms of surgical management, and may also affect visual function negatively.
doi:10.4328/acam.6037 fatcat:35cnyjrc3ngxth3a4wkoygbrbi